Dr. Manjula Reddy led the team at the Centre for Cellular & Molecular Biology (CCMB) during this research. They have discovered a new enzyme called ‘scissors enzyme’.
At a press conference on Tuesday, CCMB director Rakesh Mishra and senior scientist Manjula Reddy clarified that it is crucial to know how cells grow in bacteria to understand the anti-bacterial resistance to currently available antibiotics.
Key finding In this research according to "Jagran Josh"
- Dr Manjula Reddy and her team discovered that by blocking ‘scissors enzyme’ from functioning, new ways to target microbes could be found, leading to a new wave of antibiotic drug.
- Other bacteria, too, have the same enzyme working on cell division as the cell wall is fundamental for bacterial growth and division.
- The new enzyme offers a potential for a new drug delivery route to arrest the anti-bacterial resistance through existing antibiotic drugs.
Right now, the lab of Dr. Reddy has been working on how coli bacteria cells function, grow and divide to understand diseases like cholera, leprosy, tuberculosis.
The next step of the Centre for Cellular & Molecular Biology (CCMB) will be to find out the molecule of the enzyme endo-pepcidine and It has to be followed by the drug trials to unravel a new combination of drugs to replace existing antibiotics. It is difficult to forecast a time frame.
What is Centre for Cellular and Molecular Biology
- The Centre for Cellular & Molecular Biology (CCMB) is a premier research organization in frontier areas of modern biology which is located in Hyderabad.
- The objectives of CCMB are to conduct high quality basic research and training in frontier areas of modern biology, and promote centralized national facilities for new and modern techniques in the inter-disciplinary areas of biology.
- CCMB has got the Federation of Indian Chambers of Commerce and Industry (FICCI) Award for Outstanding Achievement in Science & Technology.
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